An Introduction to General Virology by Thomas M. Bell (Auth.)

By Thomas M. Bell (Auth.)

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Chang, H. , Huang, Y. , Wang, K. C. (1957) Chinese Med. J. 75, 429. 6. Burnet, F. M. (1936) Spec. Rep. Series, Med. Res. Council, London, No. 220. 7. Cox, H. R. (1952) Ann. Y. Acad. Sei. 55, 236. 8. Hirst, G. K. (1945) Proc. Soc. Exp. Biol. Med. 58, 155. 9. Burnet, F. M. (1940) Brit. J. Exper. Path. 21, 147. 10. Beveridge, W. I. , Burnet, F. M. (1946) Spec. Rep. Series, Med. Res. Council, London, No. 256. 11. Levens, J. , Enders, J. F. (1945) Science, 102, 117. 12. Enders, J. , Peebles, T. , Holloway, A.

Although the production of substances which will inhibit viral multiplication is relatively simple, to find one which will selectively prevent viral growth and at the same time leave the host intact is much more difficult. Many compounds, both natural and synthetic, will inhibit viral multiplication in vitro but almost without exception they have little or no effect in the intact host when administered in doses which are not toxic. The naturally occurring compounds are similar to the antibacterial antibiotics, while the synthetic compounds are analogues of such essential metabolites as purine and pyrimidene bases and amino acids.

Paul, J. (1960) "Cell and Tissue Cultures", 2nd ed. E. & S. , Edinburgh & London. 13. Morgan, J. , Morton, H. , Parker, R. C. (1950) Proc. Soc. Exp. Biol. Med. 73, 1. 1. 2. 3. 4. 5. 6. 7. 8. 9. 10. 11. TISSUE CULTURES 35 14. Eagle, H. (1955) Science, 122, 501. 15. Bell, T. M. (1962) Scot. Med. J. 7, 85. 16. Rowe, W. , Huebner, R. , Gilmore, L. , Parrott, R. H^ Ward, T. G. (1953) Proc. Soc. Exp. Biol. Med. 84, 570. 17. Bell, T. , Steyn, J. H. (1962) Brit. Med. J. 2, 700. 18. Farrell, L. , Franklin, A.

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